Division of Viral Respiratory Infections in Children

Division Lead — Vladimir P. Drinevsky, Dr.Med.Sci.

Phone: +7 (812) 234–09–67

The Division of Viral Respiratory Infections in Children was formed in 1967 with the aim of studying etiology, pathogenesis and clinical picture of influenza and ARI in children, producing new diagnostic techniques, prevention and therapy schemes. The division is based on №4 St. Olga Municipal Hospital and №5 Filatov Children’s Clinical Hospital in St. Petersburg.

Primary Activities:

Providing care for children diagnosed with influenza and ARI
Studying clinical picture (including etiology and disease localization) of influenza and other upper respiratory tract infections in children
Developing criteria for influenza prognosis
Evaluating efficacy of diagnostic tests for respiratory infections in children
Studying safety and efficacy of antiviral preparations used for treatment and prophylaxis of influenza and ARI in children
Studying safety and efficacy of novel live and inactivated influenza vaccines and vaccine strain candidates
Maintaining clinical residency program for pediatric infectologists
Organizing and taking part in conferences and workshops on the topics of clinical picture, treatment and prophylaxis of infectious diseases in children
Reading lectures for physicians working in municipal health centres
Compiling guidelines for diagnosis and therapy of influenza in children

Notable Achievements:

Using data on the etiology, clinical and laboratory features of viral infections in children, priority prophylactic measures were established
The role of mycoplasma pneumonia infection in recurrent and chronic pulmonary diseases in children with background pathologies was determined.
The role of coronavirus infection in acute respiratory pathology was examined, its’ clinical and laboratory properties during respiratory disease affecting both respiratory and digestive tracts was studied
Extensive studies of course of influenza and ARI in sickly children were conducted and criteria for prescribing interferons, interferon inductors and adaptogens produced.

Patents:

Preparation for influenza treatment (combined use of Rimantadine and a vasodilatory medication which inhibits phosphodiesterase and causes cAMP accumulation in cells). Patent № 200310549515 (005737)
Technique for rapid diagnosis of rotavirus infection on upper respiratory swabs. Dry Fluorescent Immunoglobulin. Patent application № 2009116698
Technique for forecasting severity, possibility of complications and course of ARI in children.

Theses 1999–2009: Dr.Med.Sci. Theses

V.P. Drinevsky. Evaluation of Safety and Efficacy of Novel Preparations for Treatment And Specific Prophylaxis Of Influenza In Children. 1999
L.V. Osidak. Acute Mixed Respiratory Infections in Children. 2001
Reading lectures for physicians working in municipal health centres

Theses 1999–2009: PhD Theses

O.I.Afanasyeva. High Titer Direct Action Immunoglobulins in ARI Therapy In Children. 1999
E.G. Koroleva. Acute Respiratory Mycoplasmosis and Its’ Role in the Cause of Bronchial-Pulmonary Pathology. 2003
E.G. Golovacheva. Clinical and laboratory basis for use of immune correcting therapy against respiratory syncytial infection in children. 2003
F.V. Sukhovetskaya. Clinical and Laboratory Diagnosis of Acute and Persistent Viral Respiratory Infections in Children. 2004
A.Ya. Muradyan. Role of Rotavirus Infection in Acute Respiratory Tract Pathology. 2005
E.Va. Obraztsova. Use of Interferon and Interferon Inductors against Influenza in Children. 2007
E.A. Dondurei. Etiology and Clinical Laboratory Features of Acute Viral Infections with Combined Infection of Respiratory and Digestive Tracts in Children. 2007
E.S. Erman. Evaluation of Clinical and Epidemiological Efficacy of Novel Preparations for Prevention and Treatment of Influenza and ARI in Children. 2009

Selected Publications:

L.M. Tsybalova, E.V. Esaulenko, T.A. Vetrov, L.V. Osidak, I.Ye. Korenyako. Protection of the Population against Influenza. Regional Targeted Medical Program. 2006. In Russian
L.V. Osidak , V.P. Drinevsky, I.M. Vorontsov, A.N. Galustyan, O.A. Drobachenko et al. Influenza In Children. Clinical and Pathogenetic Properties, Common Techniques of Diagnosis and Therapy. Guidelines. 2006. In Russian
L.V. Osidak , V.P. Drinevsky, E.S. Erman, E.G. Koroleva, O.I.Afanasyeva et al. «Lesmin» Coniferous Tablets. Use of Lesmin for Influenza and ARI Therapy Enhancement. 2004. 24p. In Russian
L.V. Osidak, E.S. Erman, I. Alexandrovich, O.I.Afanasyeva, E.G. Koroleva et al. «Fitolon» Dietary Supplement Based On Chlorophyll Copper Derivatives. Use for Health Improvement and Therapy. 2006. 32p. In Russian
A.A. Sominina, L.M.Tsybalova, I.G. Marinich, L.V. Osidak, M.K. Erofeeva et al. National Influenza Pandemic Preparedness Plan. 2006. 114p. In Russian
L.V. Osidak, A.Ya. Muradyan, N.B. Rumel, V.P. Drinevsky. Coronavirus Infection. Etiology, Epidemiology, Clinical Laboratory Featrues, Antiviral Therapy. Reference book for physicians. 2007. 64p. In Russian
V.N. Timchenko, V.P. Drinevsky, L.V. Osidak. Chapter for pediatrics faculty textbook «Childhood Infections». 2008. p191–195 In Russian
L.V. Osidak, V.P. Drinevsky. Chapter 6.2 in the guidebook «Airborne Infections in the Practice of Pediatrician and Family Physician». 2007. p333–339 In Russian
L.V. Osidak, E.A. Dondurei, V.P. Drinevsky. Acute Viral Infections Affecting Both Respiratory and Digestive Tracts. 2007. St. Petersburg. Pharmstandard. 89p. In Russian
L.V. Osidak, V.P. Drinevsky, P.Ya Gaponyuk. Guidebook for Physicians. Grippferon. 2009. 60p. In Russian

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